Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients
نویسندگان
چکیده
منابع مشابه
Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
Bladder cancer (BC) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. MiRNAs expression has noticeable role in bladder tumorigenesis. The purpose of this study was to assess miR-200c, miR-30b and miR-141 in tissue samples of patients with BC and healthy adjacent tissue samples and their association with muscle invasion, grade...
متن کاملevaluation of mir-141, mir-200c, mir-30b expression and clinicopathological features of bladder cancer
bladder cancer (bc) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. mirnas expression has noticeable role in bladder tumorigenesis. the purpose of this study was to assess mir-200c, mir-30b and mir-141 in tissue samples of patients with bc and healthy adjacent tissue samples and their association with muscle invasion, grade...
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Circulating microRNAs have been recognized as promising biomarkers for the detection of lung cancer. The objective of this study was to evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung cancer. Plasma samples from 47 non-small-cell lung cancer patients and 41 cancer-free subjects were evaluated for...
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The role of microRNAs (miRs) is shown as a biomarker whose expression level changes have been associated with cancer development and progression. Circulating miRNAs have been postulated as biomarkers for breast cancer. Detection and diagnosis of miRNA markers could provide an improved and sensitive method in the clinical application. In this study, we applied and improved the effective approach...
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Within the multicenter SUCCESS trial, we investigated the association of plasma microRNAs with different subtypes of invasive breast cancer.Six miRs (miR-16, miR-27a, miR-107, miR-130a, miR-132 and miR-146a) were selected from microarray profiling and further validated in plasma of 111 breast cancer patients before and after chemotherapy and 46 healthy women by quantitative real-time PCR.Plasma...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-16112-y